DFS Shared Folder Permissions - which permission is best practice?

When I create the DFS namespace the wizard allows me to edit settings and choose various permissions.  First of all, I do understand Share and NTFS permissions.  My question is related just to this initial DFS names space share (which I aptly called\\domainname\dfs).  I chose "Administrators have full access; other users have read and write permissions.  My thinking here is that we can always locked them down further down as we add folders point to various volumes.

Any Problems or Caveats with this appoach.

Also we point to NetApp files that have their own ABE implementation.

Thanks

-David

David W King