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Windows Server 2012 R2 File Server best practice and design considerations

Hi All,

Can anyone here share some best practice for building Windows Server 2012 R2 File Server for 1000+ users ?

initially the home drive H:\ will be 2 TB NTFS and the file share S:\ drive will be 4 TB NTFS minimum.

I'll enable the De-duplication, Compressionand the drive encryption (Bit locker) for added security mandated by the PCI-DSS compliance. On top of this, does the De-Duplication feature still works with Symantec Enterprise Vaultfile archiving for all files not accessed in the past 2 years as well ? 

Note: The server will be deployed on VMware virtual machine.


/* Server Support Specialist */



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